Mean blood pressure (MBP) (A, C and E) and heart rate (HR) (B, D and F) were recorded 5 min before and 60 min after placement in a metabolic cage for adult offspring of dams that were either undisturbed during pregnancy (black) or received daily third trimester injections of saline (grey) or CBX (white). In (A and B) only male results are presented, with offspring of dams receiving standard drinking water denoted by squares and offspring of dams receiving tempol during pregnancy denoted by circles. n = 5 male undisturbed, n = 9 male saline (n = 3 weaned to a hypercaloric diet), n = 13 male CBX (n = 3 weaned to a hypercaloric diet), n = 5 male undisturbed–tempol, n = 6 male saline–tempol, n = 6 male CBX–tempol, n = 12 female saline (n = 6 weaned to a hypercaloric diet), n = 11 female CBX (n = 6 weaned to a hypercaloric diet); *P < 0.05 or **P < 0.01 compared with undisturbed; †P < 0.05 or ‡P < 0.01 compared with no tempol.