Fig. 3.

Left: Platelet images of the fixed samples at eight different times. (B) State of activation and 1st filopodia extrusion, (C) state of blebbing, (F and G) filopodia extrusion. Scan range: 15 μm. Right: Corresponding diagram of the percentage of pseudopodia area to total platelet area (y-axis) plotted against time (x-axis). The maximum of the first filopodia formation was visible after about 25 ± 5 min after incubation and the maximum of the second filopod extrusion was observed after 2 h 15 ± 21 min. The scheme on top of the diagram accentuates the distinctive states of shape change.