Table 3.
Serum electrolytes, BUN and serum creatinine at various doses of spironolactone
| n | Sodium | Potassium | co2 | Cl | BUN | Creatinine | |
|---|---|---|---|---|---|---|---|
| mEq/1 | mEq/1 | mEq/1 | mEq/1 | mg/dl | mg/dl | ||
| Baseline | 18 | 135.5±3.3 | 4.0±0.5 | 26.1±3.6 | 98.7±4.2 | 28.2±14.7 | 1.3±0.5 |
| 50 mg | 16 | 135.3±3.0 | 4.0±0.5 | 26.3±2.1 | 99.3±4.2 | 25.3±15.9 | 1.2±0.4 |
| 75 mg | 9 | 132.7±2.3 | 3.9±0.6 | 24.8±2.4 | 96.1±3.9 | 29.6±13.4 | 1.5±0.5 |
| 100 mg | 8 | 134.8±3.0 | 4.0±0.3 | 23.9±2.1 | 100.6±1.6 | 27.1±14.4 | 1.4±0.5 |
| 125 mg | 2 | 134.0±5.7 | 4.3±0.1 | 26.0±1.4 | 98.5±4.9 | 15.0±4.2 | 1.0±0.4 |
| 150 mg | 1 | 140 | 3.7 | 25.0 | 102 | 9 | 0.7 |
| 200 mg | 2 | 135.5±3.5 | 4.2±0.3 | 25.5±4.9 | 99.0±4.2 | 14.5±0.7 | 1.0±0.3 |