Table 1.
Description of repeated measurements made at a total of 6 treatment sites on the upper arms of healthy human volunteers.
| Dry Ag/AgCl electrodes | Gel Ag/AgCl electrodes | |||
|---|---|---|---|---|
| Light pressure (n = 3 sites) | Direct pressure (n = 3 sites) | Light pressure (n = 3 sites) | Direct pressure (n = 3 sites) | |
| Pre-MN | 9 measurements | 9 measurements | 9 measurements | 9 measurements |
| One-time MN treatment (50 MN array applied twice) | One-time MN treatment (50 MN array applied twice) | |||
| Post-MN | 9 measurements | 9 measurements | 9 measurements | 9 measurements |
| Total1 | 36 total measurements per subject (18 measurements of intact skin baseline; 18 measurements of MN-treated skin) | 36 total measurements per subject (18 measurements of intact skin baseline; 18 measurements of MN-treated skin) | ||
1
All measurements were made on skin sites that had been pre-hydrated under blank occlusive patches overnight. The same measurement techniques were used in the Yucatan pig and the hairless guinea pigs, with additional measurements made on non pre-hydrated skin in the animal models.