Table 1.

Effects of obesity, P. balsamifera, and salicortin treatments on body and organ weights at sacrifice.

	DIO	P. balsamifera 125 mg/kg	P. balsamifera 250 mg/kg	DIO	Salicortin 12.5 mg/kg
Body Weight	138 ± 1†	120 ± 7*	131 ± 3	142 ± 2†	130 ± 3§
Retroperitoneal Fat Pad	229 ± 12†	190 ± 28	209 ± 20	242 ± 13†	218 ± 10
Epididymal Fat Pad	77 ± 3†	98 ± 17	103 ± 5*	97 ± 2	149 ± 11§
Brown Adipose tissue	189 ± 14†	136 ± 22 P = 0.057	168 ± 14	200 ± 6†	170 ± 11§
Liver Weight	167 ± 6†	108 ± 12*	122 ± 10*	166 ± 9†	118 ± 7§
Total Kidney	111 ± 4†	93 ± 3*	104 ± 4	104 ± 2	101 ± 3

Measurements were obtained after 16 weeks of treatment with either standard diet (Chow), HFD (DIO), and for the last 8 of the 16 weeks with HFD in combination with P. balsamifera at 125 or 250 mg/kg, or with the active salicortin at 12.5 mg/kg. All values are expressed as a percentage of respective Chow controls (reference set at 100%) and represent the mean ± SEM. The number of animals for each group for the P. balsamifera protocol was: CHOW (n = 12); DIO (n = 8); P. balsamifera 125 (n = 5); P. balsamifera 250 (n = 7); and for the salicortin protocol: CHOW (n = 12); DIO (n = 7); salicortin (n = 9). ^†denotes DIO significantly different as compared to Chow (unpaired Student's t test; P < 0.05). *denotes significantly different as compared to respective DIO (one way ANOVA, Bonferroni post hoc test; P < 0.05). ^§denotes significantly different as compared to respective DIO (unpaired Student's t test; P < 0.05).