Table 4.
Diagnostic test | Sensitivity/specificity | Advantages | Disadvantages |
---|---|---|---|
Stool smear Baermann [20] | 75% | Easily obtained | Requires multiple specimens to improve sensitivity and specificity |
| |||
ELISA IgG [21] | 97% sensitivity 95% specificity |
High sensitivity High specificity |
False negatives Other filarial reactions can cause false positivity Remains positive for extended periods even after treatment |
| |||
Stool on Agar plate culture [1, 22] | 96% sensitivity | High sensitivity | Requires at least 2 days |
| |||
PCR [23, 24] | >95% sensitivity >95% specificity |
High specificity Becomes negative after successful treatment |
Not all diagnostic centers are equipped to perform test |
| |||
Luciferous immunoprecipitation System [21] |
97% sensitivity 100% specificity |
<2.5 hours High sensitivity and Specificity Seroconversion after treatment |
Not all labs have capability to perform test |