Table 4.
Items Endorsed During Initial Episode on the Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections Questionnaire
| |
PANDAS (n = 19)a |
Non-PANDAS (n = 18) |
|
||
|---|---|---|---|---|---|
| Item | n | % | n | % | p |
| Separation anxiety | 14 | 73.7 | 7 | 38.9 | 0.033b |
| Bedtime fears | 9 | 47.4 | 3 | 16.7 | 0.046 |
| Nightmares | 6 | 31.6 | 1 | 5.6 | 0.043 |
| Increase in frequency of urination | 5 | 26.3 | 0c | 0.0 | 0.023 |
| Urinary urgency | 6c | 33.3 | 0c | 0.0 | 0.009b |
| Enuresis | 8 | 42.1 | 4 | 22.2 | 0.197 |
| Sensory defensiveness | 8 | 42.1 | 7c | 41.2 | 0.955 |
| Change in food intake | 9 | 47.4 | 4 | 22.2 | 0.109 |
| Irritability | 15 | 78.9 | 8 | 44.4 | 0.031 |
| Oppositional defiant behavior | 13 | 68.4 | 4 | 22.2 | 0.005b |
| Mood swings | 16 | 84.2 | 8 | 44.4 | 0.011b |
| Inattention | 14c | 77.8 | 0 | 0.0 | 0.000b |
| Hyperactivity | 10 | 52.6 | 2 | 11.1 | 0.007b |
| Impulsivity | 14 | 73.7 | 4 | 22.2 | 0.002b |
| Abnormal hand or finger movements | 8 | 42.1 | 0 | 0.0 | 0.002b |
| Change in gait | 4 | 21.1 | 1 | 5.6 | 0.168 |
| Decline in handwriting | 11c | 61.1 | 0 | 0.0 | 0.000b |
| Decline in school performance | 16c | 88.9 | 5 | 27.8 | 0.000b |
| Decline in school attendance | 5 | 26.3 | 7c | 41.2 | 0.345 |
a
Two parents did not complete the PANDAS Questionnaire.
b
PANDAS significantly different from non-PANDAS based on family-wise Bonferroni correction.
c
One subject is missing this item.