Algorithm for the management of iron deficiency anemia in patients with IBD and other GI diseases.
Notes:aHigher levels of serum ferritin do not exclude the possibility of iron deficiency. Serum ferritin <100 μg/L may still be consistent with iron deficiency in patients with IBD;15bonly iron dextrans have a broad indication for the treatment of iron deficiency anemia.
Adapted by permission from Macmillan Publishers Ltd: [Nature Reviews Gastroenterology and Hepatology]. Stein J, Hartmann F, Dignass AU. Diagnosis and management of iron deficiency anemia in patients with IBD. Nat Rev Gastroenterol Hepatol. 2010;7(11):599-610, Copyright 2010.7
Abbreviations: Hb, hemoglobin; MCV, mean corpuscular volume; MCHC, mean corpuscular hemoglobin concentration; RDW, red cell distribution width; IBD, irritable bowel disease; CHF, congestive heart failure; GI, gastrointestinal; IV, intravenous; ESA, erythropoiesis-stimulating agent.