Table 1.

Effects of model photoprobes on transcription and cytotoxicity in PC-3 cells^a.

compound	structure	IC50 SRE.L (µM)b	% inhibition SRE.L (100 µM)b	% inhibition WST-1 (100 µM)c
3		9.9	75	0
8a		8.3	84	0
8b		11	64	0
8c		5.3	60	0
14		7.0	77	13

^aFor detailed assay descriptions, see Evelyn et al. [8–9]; ^bInhibition of Rho-pathway selective serum response element-luciferase reporter gene expression; ^cInhibition of mitochondrial metabolism of WST-1.