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. 2013 Apr 24;33(17):7130–7144. doi: 10.1523/JNEUROSCI.3576-12.2013

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Figure 8. — GPe–STN synaptic depression is not due to desensitization of postsynaptic GABA_A receptors or reduction in the concentration of released GABA. A, B, Example of unitary GPe–STN synaptic transmission during the first and 10th seconds of stimulation at 33 Hz under control conditions (A) and in the presence of the low-affinity GABA_A receptor antagonist SR95103 (B; 5 μm). Inset, The entire stimulation period. C, Population data (n = 6): mean conductance (C1), mean normalized conductance (C2), and reliability of transmission (C3) against time and box plots illustrating amplitude of IPSC1 (C4) and ratio of IPSC2:IPSC1 (C5). Scale bars in B also apply to A. *p < 0.05.