Table 3.

Hierarchical regression of the impact of stress on HIV treatment adherence

Type of stress		LEDS
Moderators		DEP SEVERITY			MDE
		B	SE	ΔR2	B	SE	ΔR2
Step 1	T1 ADH	0.40**	0.10	0.33#	0.40	0.10	0.33#
	GEND	−0.13*	0.06		−0.13*	0.06
	AGE	0.01	0.00		0.01	0.00
	SIDE	−0.04	0.04		−0.04	−0.04
	STRESS	−0.01	0.01		−0.01	0.01
Step 2	MOD	0.01	0.00	0.003	0.05	0.08	0.003
Step 3	MOD × STRESS	0.00	0.00	0.02	−0.04*	0.02	0.04*
Type of stress		CSI
Moderators		DEP SEVERITY			MDE
		B	SE	ΔR2	B	SE	ΔR2
Step 1	T1 ADH	0.40**	0.10	0.32#	0.40**	0.10	0.32#
	GEND	−0.16*	0.06		−0.16*	0.06
	AGE	0.01	0.00		0.01	0.00
	SIDE	−0.04	0.04		−0.04	0.04
	STRESS	0.00	0.01		0.00	0.01
Step 2	MOD	0.00	0.00	0.003	0.03	0.08	0.001
Step 3	MOD × STRESS	0.00	0.01	0.008	−0.07	0.03	0.04*
Type of stress		PSS
Moderators		DEP SEVERITY			MDE
		B	SE	ΔR2	B	SE	ΔR2
Step 1	T1 ADH	0.41**	0.10	0.34#	0.41**	0.10	0.34#
	GEND	−0.13*	0.06		−0.13*	0.06
	AGE	0.01	0.00		0.01	0.00
	SIDE	−0.05	0.04		−0.05	0.04
	STRESS	−0.01	0.01		−0.01	0.01
Step 2	MOD	0.00	0.00	0.004	0.04	0.08	0.002
Step 3	MOD × STRESS	0.00	0.00	0.0001	−0.02	0.03	0.00

Due to space constraints, we have not shown the variables from the previous step in each subsequent step though these were included in the analyses; T1 ADH time 1 treatment adherence, GEND Gender of participant, AGE age of participant, SIDE side effects, STRESS relevant form of stress as indicated in column headings, LEDS LEDS threat, CSI chronic stress, PSS perceived stress, DEP SEVERITY clinician-assessed depressive severity, MDE presence/absence of current Major Depressive Episode, MOD relevant moderator; MOD × STRESS interaction between moderator and life stress;

^*P <0.05;

^**P <0.01