Figure 6.
Tca8113 cells pretreated with cytokines promote tumor immune evasion in vivo. Nude mice were injected subcutaneously with 2×107 PHA-supernata nt-pretreated (points B and D) or untreated control (points A and C) Tca8113 cells, followed by an intravenous injection of tumor antigen-specific T cells (right mouse) or PBS (left mouse) at three time points. All the mice were sacrificed at the 21st day post-transplantation and images were captured. The tumors were removed and weighed. The mice shown in the images are representative of each group (n=6). Error bars represent the mean ± standard deviation of the tumor weight. *P<0.05 vs. the control Tca8113 group, which were treated with tumor antigen-specific T cells. PHA, phytohemagglutinin.