Table 3.
Univariate analysis of baseline data and outcomes of patients with or without in hospital mortality
| Variable | Mortality (n = 90) | No mortality (n = 66) | P value |
|---|---|---|---|
| Age* | 65.2 ± 17 | 55.4 ± 15.4 | <0.01 |
| Vasoactive agent infusion; days* | 2.4 ± 1 | 1.8 ± 1 | <0.01 |
| Organ dysfunctions* | 3.3 ± 1.1 | 2.9 ± 1.2 | 0.04 |
| 1, n (%) | 2 (2) | 4 (6) | 0.22 |
| 2, n (%) | 20 (22) | 26 (39) | 0.02 |
| 3, n (%) | 30 (33) | 18 (27) | 0.42 |
| 4, n (%)† | 26 (29) | 10 (15) | 0.05 |
| 5, n (%) | 12 (13) | 8 (12) | 0.82 |
| APACHE II* | 30.8 ± 5.3 | 28 ± 6 | <0.01 |
| 0–19, n (%) | 1 (1) | 3 (5) | 0.18 |
| 20–24, n (%) | 5 (6) | 9 (14) | 0.08 |
| 25–29, n (%) | 34 (38) | 29 (44) | 0.44 |
| ≥30, n (%)† | 50 (56) | 25 (38) | 0.03 |
| Presence of any baseline precaution or contraindication, n (%) | 35 (39) | 19 (29) | 0.19 |
| CRRT, n (%) | 28 (31) | 12 (18) | 0.07 |
| Mechanical ventilation, n (%) | 84 (93) | 59 (89) | 0.38 |
| Corticosteroids, n (%) | 55 (61) | 34 (52) | 0.23 |
| Infection type; n (%) | |||
| Pneumonia | 39 (43) | 21 (32) | 0.15 |
| Intra-abdominal | 26 (29) | 19 (29) | 0.99 |
| Urological | 5 (6) | 7 (11) | 0.24 |
| Skin | 8 (9) | 17 (26) | <0.01 |
| Other/unknown | 12 (13) | 2 (3) | 0.03 |
| Pathogen, n (%) | |||
| Gram positive | 20 (22) | 20 (30) | 0.26 |
| Gram negative | 21 (23) | 21 (32) | 0.24 |
| Fungal | 5 (6) | 1 (2) | 0.2 |
| Mixed | 5 (6) | 3 (5) | 0.78 |
| Unknown | 39 (43) | 21 (32) | 0.18 |
| Medical ICU, n (%)† | 46 (51) | 26 (39) | 0.15 |
| Major bleed, n (%) | 15 (17) | 8 (12) | 0.43 |
| ICU length of stay; days* | 14.1 ± 14.4 | 27.5 ± 30.6 | <0.01 |
| Hospital length of stay; days* | 17.6 ± 16.4 | 40.2 ± 35.3 | <0.01 |
Notes:
*
Data presented as mean ± SD;
†
variable selected for the multivariate logistic regression analysis. Vasoactive agents include: Norepinephrine, phenylephrine, epinephrine, vasopressin, dopamine, and dobutamine.
Abbreviations: APACHE, Acute Physiology and Chronic Health Evaluation; ICU, intensive care unit; CRRT, continuous renal replacement therapy; SD, standard deviation.