Figure 4.
Schematic rendering of different methods that can be used for whole-body fluorescence imaging. The first row shows epi-illumination geometries: (a) broad beam illumination with wide-field camera detection; (b) raster-scan illumination with wide-field camera detection, (c) raster-scan illumination and detection. The lower row of images shows the corresponding trans-illumination configurations. Not shown in the figure are configurations optimized for tomography imaging and fiber-based planar configurations.