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. 2013 Jun 11;8(6):e66720. doi: 10.1371/journal.pone.0066720

Table 2. Morphometric and echocardiographic parameters.

BW (g) HW (mg) TL (mm) HW/TL HW/BW HR (bpm) IVSd (mm) PWd (mm)
+/+ NT 24.8±1.1 116±5 18.0±0.1 6.48±0.23 4.69±0.08 694±13 0.77±0.05 0.70±0.04
+/+ Veh 28.5±2.7 139±6 18.3±0.2 7.62±0.33 4.94±0.26 728±10 0.71±0.10 0.67±0.06
+/+ Nrg 26.6±1.2 134±7 17.9±0.2 7.47±0.31 5.04±0.08 649±12 δ 0.94±0.07 δ 0.96±0.08 δ
−/− NT 24.3±0.8 128±3 17.9±0.1 7.13±0.14 5.27±0.12 # 646±25 0.74±0.02 0.74±0.03
−/− Veh 25.1±1.1 132±6 17.8±0.2 7.39±0.28 5.27±0.13 # 690±23 0.80±0.07 0.83±0.07
−/− Nrg 23.8±0.5 128±3 17.7±0.1 7.22±0.15 5.38±0.05 # 691±15 0.85±0.04 δ 0.99±0.04 δ

N = 4 or more. Abbreviations are: BW, body weight; HW, heart weight; TL, tibial length; HR, heart rate; IVSd, interventricular septal wall diameter; PWd, posterior wall diameter. Significance determined using GraphPad software. #P<0.05 compared with non-treated wildtype (+/+ NT) hearts by 1 way ANOVA, Newman-Keuls multiple comparisons test; δP<0.05 compared with pre-treatment values (not shown) by paired t-test, parametric, one-tailed.