Table 1. Socio-demographic and clinical characteristics of HC and PD subjects.

Characteristics		HC (n = 80)	PD (n = 80)	p value
Gender (men %)		50%	50%	–
Age (years)		59.5±9.5	59.2±9.9	0.833
Education (years )		12.3±3.8	12.6±3.7	0.645
MMSE (score)		29.2±1.2	28.5±2.1	0.0122
BDI total (score)		5.3±4.3	10.1±8.0	<0.0001
BDI PSY (score)		3.1±2.9	5.6±5.2	0.0003
BDI SOM (score)		2.2±2.0	4.5±3.3	<0.0001
Disease duration (years)		–	4.6±3.8	–
Hoehn & Yahr (%)	stage 1	–	25%	–
	stage 1.5	–	25%	–
	stage 2	–	32.9%	–
	stage 2.5	–	11.8%	–
	stage 3	–	5.3%	–
	stage >3	–	0%	–
Hoehn & Yahr stage (score)		–	1.74±0.57	–
UPDRS III (score)		–	17.4±9.5	–
L-dopa (mg/day)		–	263.2±287.1	–
DA-LED (mg/day)		–	202.0±271.0	–
Total LED (mg/day)		–	465.2±389.8	–

Values are expressed as mean ± SD or percentage of subjects (%).