Table 3. Significant group difference in GM volume.
Controls > Patients | Patients > Controls | |||
Z-level | Size (cm3) | Coordinates | ||
Left middle frontal gyrus | 4.3 | 1.9 | 25–11 59 | |
Anterior cingulate cortex (BA 32) # | 3.4 | 0.5 | −39 6 46 | NONE |
Right middle frontal gyrus | 5.0 | 2.1 | −2 31 13 |
# Cluster showing a significant group difference when using a limbic mask comprising the anterior cingulate cortex, the mPFC, the insular cortex, the hippocampus and the amygdala, using peak threshold at p = 0.001, FDR corrected at p<0.05. The other clusters were calculated with same level of significance, but using the entire brain as search space (no a priori hypothesis).
No group differences were observed in white matter volumes and no significant clusters were detected when reversing the contrast (using the contrast: stressed patients – controls).