Table 3. Significant group difference in GM volume.

	Controls > Patients			Patients > Controls
	Z-level	Size (cm3)	Coordinates
Left middle frontal gyrus	4.3	1.9	25–11 59
Anterior cingulate cortex (BA 32) #	3.4	0.5	−39 6 46	NONE
Right middle frontal gyrus	5.0	2.1	−2 31 13

# Cluster showing a significant group difference when using a limbic mask comprising the anterior cingulate cortex, the mPFC, the insular cortex, the hippocampus and the amygdala, using peak threshold at p = 0.001, FDR corrected at p<0.05. The other clusters were calculated with same level of significance, but using the entire brain as search space (no a priori hypothesis).

No group differences were observed in white matter volumes and no significant clusters were detected when reversing the contrast (using the contrast: stressed patients – controls).