Figure 8. Nfix^+/− mice exhibit normal motor function and anxiety-related behaviour.

Performance of adult wild-type and Nfix ^+/− mice during the open-field test (A, B) and the elevated plus maze (C, D). In the open-field test there was no effect of genotype on the distance travelled over the 10 minute test period (p>0.5; A), or on time spent in the centre of the test apparatus (p = 0.43; B). In the elevated plus maze no effect of genotype was observed on the percentage of total trial time spent on the open arms, closed arms or the centre position of the maze (p>0.5; C), or on number of open arm entries (p = 0.29; D). (Nfix ^+/+: n = 20, Nfix ^+/−: n = 26).