Table 2. Randomized controlled trials of MBCT.
| Study | N | Type Participant | Mean Age | % Male | No. of Treatment Sessions | Control Group(s) | Main Outcome |
|---|---|---|---|---|---|---|---|
| Teasdale et al., 2000 | 145 | Patients in remission from depression | 43 | 24 | 8 2-hr sessions | TAU (69) | MBCT > TAU: reduction in rate of depressive relapse/recurrence for patients with 3 or more previous relapses, but not patients with 2 or fewer episodes |
| Williams et al., 2000* | 45 | Patients in remission from depression | 44 | 51 | 8 2-hr sessions | TAU (20) | MBCT > TAU: reduction in generality of autobiographical memory |
| Teasdale et al., 2002* | 100 | Patients in remission from depression | 44 | 22 | 8 2-hr sessions | TAU (48) | MBCT > TAU: increase in metacognitive awareness |
| Ma & Teasdale, 2004 | 75 | Patients in remission from depression | 45 | 24 | 8 2-hr sessions | TAU (38) | MBCT > TAU: reduction in rate of depressive relapse/recurrence for patients with 3 or more previous relapses, but not patients with 2 or fewer episodes |
| Crane et al., 2008 | 68 | Patients in remission from depression and with a history of suicidal ideation or behavior | NR | NR | 8 2-hr sessions, 1 all-day session | WL (35) | MBCT + TAU > TAU: less increase in actual-ideal self discrepancy |
| Kuyken et al., 2008 | 123 | Patients in remission from depression and with a history of 3 or more depressive episodes | 49 | 24 | 8 2-hr sessions | m-ADM (62) | MBCT = m-ADM: rate of depressive relapse/recurrence; MBCT > m-ADM: reductions in residual depressive symptoms & psychiatric comorbidity, increase in quality of life |
| Barnhofer et al., 2009 | 31 | Patients with recurrent depression and a history of suicidal ideation | 42 | 25 | 8 2-hr sessions | TAU (15) | MBCT > TAU: reductions in depressive symptoms & number of patients meeting full criteria for depression at post-treatment |
| Hepburn et al., 2009 | 68 | Patients in remission from depression and with a history of suicidal ideation | 44 | NR | 8 2-hr sessions, 1 6-hr session | TAU (35) | MBCT > TAU: reductions in depressive symptoms & thought suppression |
| Hargus et al., 2010 | 27 | Depressed patients with a history of suicidal ideation or behavior | 42 | 33 | 8 2-hr sessions | TAU (13) | MBCT + TAU > TAU: reduced depression severity, increased meta-awareness of & specificity of memory related to previous suicidal crisis |
| Williams et al., 2008 | 68 | Patients with unipolar and bipolar disorders | NR | NR | 8 2-hr sessions, 1 all-day session | WL (35) | MBCT > WL: reduced depressive symptoms in both subsamples & less increase in anxiety among bipolar patients |
| Bondolfi et al., 2010 | 60 | Patients in remission from depression and with a history of 3 or more depressive episodes | 47 | 28 | 8 2-hr sessions | TAU (29) | MBCT + TAU > TAU: prolonged time to relapse; Tx = TAU: rate of depressive relapse/recurrence |
| Godfrin & Heeringen, 2010 | 106 | Recovered depressed patients with a history of 3 or more depressive episodes | 46 | 19 | 8 2.75-hr sessions | TAU (54) | MBCT + TAU > TAU: reduced rate of depressive relapse/recurrence, depressive mood & quality of life |
| Piet et al., 2010 | 26 | Patients with social phobia | 22 | 30 | 8 2-hr sessions | GCBT (12) | MBCT = GCBT: reductions in symptoms of social phobia |
| Thompson et al., 2010 | 53 | Patients with epilepsy and depressive symptoms | 36 | 19 | 8 1-hr sessions | TAU (27) | MBCT > WL: reduction in depressive symptoms |
*
Notes. = findings reported were drawn from a subset of sample in Teasdale et al., 2000's study.
NR = Not Reported; NI = No Intervention; WL = Wait-list; TAU = Treatment As Usual; m-ADM = Maintenance Anti-depressant Medication; GCBT = Group Cognitive-Behavioral Therapy.