Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Alternate FEN1 cleavage. Substrates with trinucleotide repeats or other self-complementary sequences can equilibrate to contain (a) both 5′ and 3′flaps, (b)only a 5′ flap, or (c) a configuration producing an expansion intermediate by creating a hairpin and a flap with an alternate FEN1 cleavage site. The green arrows indicate the sites of FEN1 cleavage.
