Effect of E2 status and psychophysical stress on masseter muscle EMG activity evoked by intra-TMJ injections of ATP. A. TMJ-evoked masseter muscle EMG activity increased significantly in a dose-dependent manner after FS and sham conditioning and under HE and LE conditions. B. Response latency decreased significantly in all treatment groups. Sample sizes: HE-FS = 9, HE-sham = 8, LE-FS = 8, LE-sham = 8 rats. **P < 0.01 versus PBS; a = P < 0.05, b = P < 0.01 versus sham; + = P < 0.05, ++ = P < 0.01 HE- versus corresponding LE-treated group.