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. Author manuscript; available in PMC: 2014 Jun 15.
Published in final edited form as: J Immunol. 2013 May 6;190(12):6287–6294. doi: 10.4049/jimmunol.1300431

Figure 4. P. murina-specific antibody levels are elevated in serum of BL/6 Stat4-/-, but not Balb/c Stat4-/-, mice.

Figure 4

(A/B/C) C57BL/6 WT and Stat4-/- mice and (D/E/F) Balb/c WT and Stat4-/- mice were administered 2 × 105 Pneumocystis cysts via intratracheal inoculation followed by bleeding mice weekly for 28 days. P. murina-specific (A/D) IgG1, (B/E) IgG2b, (C) IgG2c (C57BL/6) and (F) IgG2a (Balb/c) and were determined by ELISA. Cumulative data are shown from three independent studies with n = 3-4 mice/group per study. Data is expressed as the mean per group of the natural log of the dilution at which the OD450 is 0.1 + SEM. * and ** represent P values of < 0.05 and < 0.01, respectively (Unpaired two-tailed Student's t test).