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. Author manuscript; available in PMC: 2014 Jun 15.
Published in final edited form as: J Immunol. 2013 May 6;190(12):6287–6294. doi: 10.4049/jimmunol.1300431

Figure 6. Lower Th2 cytokine levels in plasma correlate with Pneumocystis jirovecii colonization in HIV-infected individuals.

Figure 6

(A) Plasma was collected from a cohort of HIV-infected individuals who were subsequently confirmed to be colonized with P. jirovecii via nested PCR (n = 50). Controls included HIV-infected individuals who were negative for P. jirovecii by nested PCR (n = 53). T helper cytokine levels were quantified in clarified co-culture supernatants by Bio-Plex. Data is expressed as pg/ml (each symbol represents a single individual. * and ** represent P values of < 0.05 and < 0.01, respectively (Non-parametric two-tailed Mann-Whitney test). (B) Percentage of P. jirovecii colonized vs. non-colonized individuals with detectable Th2 cytokines above the median for each. * and ** represent P values of < 0.05 and < 0.01, respectively (Chi square test). (C) CD4 cell numbers in peripheral blood of P. jirovecii colonized vs. non-colonized HIV-infected individuals.