Table 1.

Apoptotic cell processing defects associated with disease phenotypes

Genes involved	Disease associated
1. Find-me signals
CX3CL1	Neurodegenerative disease [179]
CX3CR1	Atherosclerosis [180]
2. Tickle-me signals
Mer	SLE [40, 42] Glomerulonephritis [181] Atherosclerosis [182]
MFG-E8	Glomerulonephritis, SLE [39, 56] Neurodegenerative disease [183, 184]
GAS-6	SLE [185]
C1q	SLE [186]
TIM4	Mild autoimmunity [36]
3. Engulf (eat)-me signal
ELMO1	Type-1 diabetes [187]
4. Post-engulfment signals
LXRα/β	SLE [188]
PPARδ	SLE [189]
DNase II	Arthritis [59]