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. Author manuscript; available in PMC: 2014 Jul 5.
Published in final edited form as: Eur J Pharmacol. 2013 Apr 30;711(0):50–56. doi: 10.1016/j.ejphar.2013.04.020

Figure 1. BRL37344 decreases the amplitude and muscle force of the 20 Hz EFS-induced contractions in rat DSM isolated strips.

Figure 1

A) This original DSM tension recording illustrates BRL37344 (10 nM–100 µM) inhibitory effects on 20 Hz EFS-induced contractions. This particular original recording shows a bit greater degree of inhibition than the average observed. B) This original DSM tension recording illustrates the attenuation of BRL37344 (10 nM–100 µM) inhibitory effects on 20 Hz EFS-induced DSM contractions in the presence of SR59230A (10 µM). C-D) These cumulative concentration-response curves illustrates SR59230A antagonistic effects against BRL37344 inhibitory effects on EFS-induced contraction amplitude and force, respectively (n=11, N=6; *P<0.05).