TABLE 2.
Expression change in response to diet for nine chr 11 QTL candidate genes in low and high LDL-C responders
| Direction of Change of Gene Expression |
|||
| Gene | Physical location (Mb) [Feb. 2009 (GRCh37/hg 19)] | Low LDL-C liver | High LDL-C liver |
| ACVR1B | 52.3 | — | ▾ |
| KRT80 | 52.5 | ▴ | ▴ |
| KRT73 | 53.0 | — | ▾ |
| TENC1 | 53.4 | ▴ | — |
| CALCOCO1 | 54.1 | — | ▴ |
| DGKA | 56.3 | — | ▴ |
| ERBB3 | 56.4 | — | ▾ |
| MYL6B | 56.5 | — | ▾ |
| GLS2 | 56.8 | ▴ | ▴ |
▴ (triangle up filled) indicates upregulation, ▾ (triangle down filled) indicates downregulation, and — indicates no detectable change in gene expression.