Figure 2.

Global parameters describing locomotion in wild-type, mutant, or drug-treated larvae. (A) Distribution of global parameters of movements for 5–7 dpf WT larvae. From left to right: Number of oscillations per movement, TBF in Hz across all movements, duration of each movement in ms, heading direction range in degrees, distance traveled per movement in mm, speed in mm/s during each movement (eight videos, 420 larvae, six clutches, 5–7 dpf, 44,688 movements). All values were calculated per movement. (B) Effect of the glycinergic receptor antagonist strychnine on the global parameters of movements. White circles are before application, gray are after application (two videos, 42 larvae for each condition, two clutches, 6–7 dpf, 10,459 movements). (C) Effect of the atoh7 mutation on the global parameters characterizing movements (four videos, 112 mutants atoh7^−/−, and 112 control siblings, four clutches, 6 dpf). For (B,C): error bars are standard errors of the mean and statistics were calculated per larva.