Figure 2. Crystal structures of Nup188C.
(A) Schematic diagram of full-length Myceliophthora thermophila Nup188C with details about the subdomain arrangement. The crystallized fragments is boxed and gradient-colored in blue with helical HEAT- and ARM-repeats indicated. (B) Crystal structure of the C-terminal part of Nup188, gradient-colored as in (A), with the inner helices in pale-yellow. (C) Superposition of chains A (blue) and B (gray) of Nup188C shows the flexibility seen in the crystal, in which the outer helices of chain B move by 3–4 Å relative to the helices in chain A.