Table 2. Laboratory Findings in Biotin and Control Groups.

Outcome variable	Control (n=35)	Biotin (n=35)	p value Mean Df±srd(CI 95%)
HgA1c (%)
Baseline	9.39±1.58	9.84±1.80	0.290
After 3 mo.	10.11±1.68	8.88±1.73
p value	<0.001	<0.001	<0.001
Mean Df±srd(CI 95%)	-0.714±0.049(-0.906,-0.523)	0.959±0.142(0.672,1.247)	1.673±0.170(1.334,2.014)
FBS (mg/dl)
Baseline	274.85±74.40	275.91±65.76	0.823
After 3 mo.	276.47±50.67	226±41.31
p value	0.818	<0.001	<0.001
Mean Df±srd (CI 95%)	-1.617±6.988(-15.834,12.599)	49.914±6.495(36.71,63.11)	50.987±6.786(-25.845,67.910)
Chol (mg/dl)
Baseline	149.18±22.54	149.69±23.56	0.928
After 3 mo.	156.07±18.77	148.6±21.09
p value	0.004	0.449	0.002
Mean Df±srd(CI 95%)	-6.893±2.201(-11.409,-2.377)	1.095±1.434(-1.800,3.991)	-7.999±2.510(-12.998,-2.977)
TG (mg/dl)
Baseline	100.18±16.61	96.48±36.20	0.565
After 3 mo.	103.86±14.69	90.43±27.54
p value	0.025	0.055	0.017
Mean Df± srd(CI 95%)	-3.679±1.552(-6.862,-0.495)	6.048±3.063(-0.138,-12.234)	9.726±3.957(1.810,17.642)
LDL (mg/dl)
Baseline	74.25±8.39	75.69±10.71	0.551
After 3 mo.	76.64±7.95	73.12±8.90
p value	0.019	0 .016	0.001
Mean Df±srd(CI 95%)	-2.393±0.963(-4.368,-0.418)	2.571±1.028(0.496,4.647)	4.964±1.484(2.001,7.927)
HDL (mg/dl)
Baseline	42.57±4.19	43.38±5.57	0.515
After 3 mo.	41.54±3.74	42.64±5.01
p value	0.002	0.235	0.666
Mean Df±srd(CI 95%)	1.036±0.311(0.398,1.673)	0.738±0.613(-0.499,1.975)	-0.298±0.793(-1.881,1.286)

TG: triglyceride; Chol: cholesterol; HDL: high density lipoprotein cholesterol; LDL: low density lipoprotein cholesterol; Mean Df: Mean Difference; srd: Std. Error Difference; CI: Confidence Interval of the Difference