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. 2013 May 28;2013:741804. doi: 10.1155/2013/741804

Figure 3.

Figure 3

Ultra-high dose HOCbl consistently improves survival in experimental endotoxaemia. Mice (n = 12 per group: 2 Cbl active treatment groups plus 1 LPS-only group) were treated with HOCbl, following two distinct protocols, +40 mg/kg at 2 h and +4 h post LPS+D-Gal, and +80 mg/kg at only +2 h following LPS (0.1 mg/kg i.p.) + D-Galactosamine (1 g/kg i.p.). Impact on lethality was followed for a total of 5 days. *P < 0.05 for HOCbl at both doses, when tested against LPS+D-Gal (n = 12), using the Chi-square test. *P < 0.01 for HOCbl (80 mg/kg) by using the Kaplan-Meier test.