Table 1.
Number of tissue inhibitor of metalloproteases (TIMP) and netrin module (NTR)-containing protein sequences, respectively, identified in each sequence dataset and listed according to taxa
| TIMPs (no. with SP) | NTR-module containing proteins (no. with SP) | |
|---|---|---|
| Nematodes |
|
|
| Ascaris suum |
3* (3) |
2 (1) |
| Brugia malayi |
- |
1 (1) |
| Dictyocaulus filaria |
1 (1) |
1 (−) |
| Necator americanus |
8** (3) |
1 (1) |
| Oesophagostomum dentatum |
2 (2) |
1 (−) |
| Trichinella spiralis |
- |
1 (1) |
| Trichuris suis |
- |
2 (−) |
| Wuchereria bancrofti |
- |
2 (−) |
| Trematodes |
|
|
| Clonorchis sinensis |
- |
1 (−) |
| Fasciola gigantica |
- |
2 (−) |
| Fasciola hepatica |
- |
1 (−) |
| Opisthorchis viverrini |
- |
4 (1) |
| Schistosoma haematobium |
1*** (1) |
5 (−) |
| Schistosoma japonicum |
- |
1 (−) |
| Schistosoma mansoni |
- |
1 (−) |
| Total | 15 (10) | 26 (5) |
The number of proteins containing a predicted N-terminal signal peptide (SP) is also indicated.
*Of these, Ascaris suum GS_04796 was up-regulated in the reproductive tissue of the adult female, while GS_21732 was up-regulated in the muscular tissue of adult males.
**Necator americanus NECAME_13168 and NECAME_07191 were up-regulated in infective L3s, while NECAME_08457 and NECAME_08458 were up-regulated in adult N. americanus, ***Schistosoma haematobium A_01727 was up-regulated in the adult male.