Table 1.
Basal clinical data of each study group, and clinical findings at IRIS onset
| N | Male/female | Age | HIV ARN copies/mL | CD4 T cells/μl | %CD8 T cells | Onset time (days) | Previous infections | Concomitant infections | |
|---|---|---|---|---|---|---|---|---|---|
| No IRIS |
17 |
16/1 |
34.6 (30.5-39.9) |
5.7 (4.9-5.9) |
73.3 (33.1-109.8) |
69 (65.3-75) |
|
PCP, pulmonary TB, hairy leukoplakia, oral candidosis, herpes simplex, MAC, community-acquired pneumonia, persistent diarrhea, chickenpox, herpes zoster, aseptic meningitis |
Herpes zoster, molluscum contagiosum, warts, xerosis, community-acquired pneumonia, MAC |
| All IRIS |
17 |
16/1 |
35.5 (31–41) |
5.4 (5–5.8) |
35 (10.5-94.5) |
74 (62–80) |
55 (35.8-70.5) |
|
|
| TB |
6 |
6 |
33.4 (27.9-35.8) |
5.2 (5.1-5.7) |
61.5 (5–132) |
76 (73–79) |
55.5 (53–56) |
Chicken pox, molluscum contagiosum, PCP, pulmonary tuberculosis, oral candidosis, MAC |
Recurrent chickenpox |
| Other IRIS |
11 |
10/1 |
36 (34.4-44.6) |
5.4 (5–5.9) |
35 (13.8-85.5) |
74 (57–84.3) |
52 (31.3-97.5) |
|
|
| HS |
1 |
|
36 |
4.3 |
185 |
77 |
35 |
Condylomata, oral candidosis |
Warts, condylomata |
| CMV |
3 |
|
30.6 (30–42) |
5 (5–5.4) |
35 (13.25-62.75) |
63 (34.5-80.3) |
56 (53–72.5) |
Pulmonary and ocular CMV, PCP, oral candidosis, HIV retinopathy, skin KS, |
Molluscum contagiosum, warts, skin KS, rash, xerosis |
| HZ |
3 |
|
46.9 (40.8-49.7) |
5.9 (5.6-5.9) |
38 (5–80) |
74 (48.3-74) |
133 (111.3-178) |
Molluscum contagiosum, PCP, MAC, cheilosis |
Community-acquired pneumonia, cheilosis |
| KS |
1 |
|
35 |
6 |
90 |
55 |
41 |
Chickenpox |
Eczema, xerosis |
| MAC | 3 | 2/1 | 35.2 (34.5-39.1) | 5.4 (4.8-5.8) | 12 (6.8-17.3) | 86 (80.8-91.3) | 28 (21.3-29.5) | PCP, chickenpox, KS, CMV retinitis, molluscum contagiosum | CMV retinitis, perivascular dermatitis |