Table 4.
Adjuvant chemotherapy regimens and relapses in 48 patients with metaplastic breast cancer
Chemotherapy regimen | Number | Patient outcome |
---|---|---|
Cyclophosphamide, methotrexate and fluorouracil |
7 |
Seven relapsed. |
(Fluorouracil), doxorubicin/anthracyclines and cyclophosphamide |
7 |
Two relapse-free at 45 and 57 months. One alive and well at 62 months after a local recurrence. Two progressed while receiving adjuvant therapy. Two relapsed. |
(Fluorouracil), doxorubicin/anthracyclines and cyclophosphamide to taxane, paclitaxel/cisplatin/carboplatin |
9 |
Five relapse-free at 30, 53, 66, 69 and 101 months respectively. Four relapsed. |
Taxane/paclitaxel, anthracyclines and cyclophosphamide |
18 |
Eight relapse-free at 55, 64, 75, 91, 108, 110, 123 and 156 months respectively. Ten relapsed. |
Taxane, anthracyclines and cyclophosphamidein combination with cisplatin/capecitabine |
4 |
Three alive and well at 17, 25 and 39 months after a local recurrence. One alive at 45 months before a local recurrence, alive at 20 months after distant metastasis. |
Paclitaxel, anthracyclines and cyclophosphamidein combination with capecitabine/vinorelbine | 3 | Three alive at 24, 29 and 41 months before a local recurrence, alive at 15, 18 and 25 months after distant metastasis. |