Table 2.
Summary of the effects of drugs on ‘binge’ eating in baboons
Candy
|
Pellet
|
|||||
---|---|---|---|---|---|---|
Seekingd
|
Seeking
|
|||||
Latency | Rewards | Takinge rewards | Latency | Rewards | Taking rewards | |
Dexfenfluraminea | ⇔ | ⇔ | ⇓ | ⇑ | ⇔ | ⇓ |
Amphetamineb | ⇑ | ⇔ | ⇓ | ⇑ | ⇔ | ⇓ |
Memantinea | ⇔ | ⇔ | ⇓ | ⇑ | ⇔ | ⇓ |
MTEPa | ⇔ | ⇔ | ⇓ | ⇔ | ⇔ | ⇔ |
Neramexanec | ⇔ | ⇔ | ⇓ | ⇑ | ⇔ | ⇓ |
CB1 antagonistb | ⇔ | ⇔ | ⇓ | ⇔ | ⇑ ⇓f | ⇓ |
indicates an increase;
indicates a decrease;
indicates no effect.
CB1, cannabinoid type 1.
Foltin R.W., Bisaga A., Danysz W., unpublished observations.
Seeking refers to responding reinforced by stimuli paired with pellets or candy that occurs before the delivery of pellets or candy.
Taking refers to responding reinforced by a pellet or a piece of candy.
Increased in males, decreased in females.