Table 3.
Potential BNP and NT-proBNP cut off levels for the assessment of systolic heart failure for all CKD subjects
|
Natriuretic peptide |
Group |
Optimal cut point (pg/ml) |
Sensitivity |
Specificity |
Positive likelihood ratio |
Negative likelihood ratio |
|---|---|---|---|---|---|---|
| % | % | |||||
| BNP |
Overall |
217 |
64.2 |
70 |
1.04 |
0.96 |
| BNP |
Overall |
254 |
61 |
75 |
1.14 |
0.90 |
| BNP |
Overall |
300 |
55 |
82.1 |
3.05 |
0.55 |
| NT-proBNP |
Overall |
799 |
91.6 |
52.6 |
1.99 |
0.16 |
| NT-proBNP |
Overall |
1536 |
84.2 |
71.6 |
4.13 |
0.30 |
| NT-proBNP | Overall | 4502 | 73.7 | 82.1 | 4.17 | 0.30 |
Abbreviations: BNP B-type natriuretic peptide, NT-proBNP amino terminal B-type natriuretic peptide, AUC area under the curve, CKD chronic kidney disease.