Table 4.
Potential BNP and NT-proBNP cut off levels for the assessment of systolic heart failure according CKD staging
|
Natriuretic peptide |
Group |
Optimal cut point (pg/ml) |
Sensitivity |
Specificity |
|---|---|---|---|---|
| % | % | |||
|
BNP |
Stage 3 CKD |
146 |
60 |
65.9 |
|
BNP |
Stage 4 CKD |
309.4 |
60 |
78.4 |
|
BNP |
Stage 5 CKD |
491 |
60 |
88.2 |
|
NT-proBNP |
Stage 3 CKD |
1505.8 |
72.2 |
92.7 |
|
NT-proBNP |
Stage 4 CKD |
7767.5 |
70 |
91.9 |
| NT-proBNP | Stage 5 CKD | 11215.2 | 94.7 | 100 |
Abbreviations: BNP B-type natriuretic peptide, NT-proBNP amino terminal B-type natriuretic peptide, AUC area under the curve, CKD chronic kidney disease.