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. 2013 May 15;4:15. doi: 10.1186/1759-8753-4-15

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Copyright © 2013 Jursch et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Transposition activity of Tc1/mariner elements upon CpG methylation. CpG-methylated (black bars) or untreated (grey) Tc1-, Himar1-, Hsmar1-, Minos-, SB-, FP-gene trap donor plasmids were co-transfected with/without transposase into HeLa cells and selected with G418. The transposition ratio was calculated by dividing the numbers of G418-resistant colonies obtained in the presence of transposase by the number of colonies obtained in the absence of transposase. Error bars are the standard deviation; the asterisk indicates that the error bar cannot be displayed for FP (±38.6). FP: Frog Prince; SB: Sleeping Beauty.