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. 2013 May 29;12:56. doi: 10.1186/1475-2859-12-56

Figure 1.

Figure 1

Synthesis of L(-)-carnitine. (A) Chemical synthesis of L(-)-carnitine and crotonobetaine. (B) Metabolism of trimethylammonium compounds in E. coli. Biotransformation of crotonobetaine into L(-)-carnitine. Abbreviations: L(-)-Car: L(-)-carnitine; Crot: crotonobetaine; γ-BB: γ-butyrobetaine; CaiT: L(-)-carnitine/crotonobetaine/γ-butyrobetaine protein transporter; CaiB: crotonobetainyl-CoA:L(−)-carnitine CoA-tranferase; CaiC: L(-)-carnitine, crotonobetaine or γ-butyrobetaine CoA-ligase; CaiD: crotonobetainyl-CoA hydratase. Adapted from [6].