Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 May 28;13:52. doi: 10.1186/1475-2867-13-52

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 Osman et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

A photomicrograph of the myocardium of a rat given DOX ( 20 mg/kg,i.p.) a :showing areas of myocytolysis(m). H&E × 400. b: showing congestion of blood vessels (arrows). H&E × 400. c: showing myocytes with cytoplasmic vacuolization (V) or fragmentation (F). Some nuclei were pyknotic (thin arrow) while others revealed chromatin margination (thick arrow). H&E × 400. d: showing hyalinization of the muscle fiber (thick arrow). Notice the congested blood vessel (thin arrow). H&E × 400. e: showing chromatin margination of some nuclei (black arrows)while others were pyknotic (white arrows). Areas empty of muscle fibers around the pyknotic nuclei were evident (thick arrow). H&E × 400.