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. 2013 Apr 24;8:10. doi: 10.1186/1745-6150-8-10

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Copyright © 2013 Laddha et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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C14 miRNAs target the glioma pathway. The biological process has been drawn by adapting the information from the KEGG pathway. mRNA names are written in dark grey boxes. The miRNAs targeting the corresponding genes are denoted by numbers and written inside circles. The miRNAs that were found to be significantly downregulated in GBM (Figure 2) has been colored in green, the ones not differentially expressed are in grey. The miRNAs are numbered according to their respective positions (5’ – 3’ direction) in the genome: hsa-miR-379 (1), -299-3p (2), -380 (3), -1197 (4), -323-3p (5), -323-5p (6), -323b (7), -758 (8), -329 (9), -543 (10), -495 (11), -654-3p (12), -654-5p (13), -376-a1 (14), -376-a2 (15), -539 (16), -382 (17), -134 (18), -668 (19), -485-3p (20), -485-5p (21), -377 (22), -541 (23), -409-3p (24), -409-5p (25), -412 (26).