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. Author manuscript; available in PMC: 2013 Jun 12.
Published in final edited form as: Neuropharmacology. 2012 Jan 27;62(7):2227–2238. doi: 10.1016/j.neuropharm.2012.01.018

Fig. 4.

Fig. 4

Cytoskeletal actin organization depends on NR2B. A, B. Changes in cytoskeletal actin organization using confocal fluorescence images of DIV 13–15 WT mouse cortical neurons treated to activate synaptic (A) or extrasynaptic (B) NMDARs in the absence of con-G, or in the presence (C, D) of 40 μM con-G. E–H. Actin organization of DIV 13–15 NR2A−/−-derived mouse cortical neurons with synaptic (E) and extrasynaptic (F) activated NMDARs in the absence of con-G, and in the presence (G, H) of 40 μM con-G. I, J. Actin organization of DIV 13–15 NR2B−/−-derived mouse cortical neurons with synaptic (I) and extrasynaptic (J) activated NMDARs in the absence of con-G.