Fig. 8.

Voltage-dependent whole cell NMDA-induced current block by Mg²⁺. Representative current–voltage (I–V) curves recorded in the absence of Mg²⁺ (black lines) and in the presence of 100 μM Mg²⁺ (red lines) in WT, NR2A^−/−, and NR2B^−/− mouse cortical neurons. The curves were normalized to the current at −100 mV in Mg²⁺-free solution. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)