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. 2013 Jun 12;8(6):e65996. doi: 10.1371/journal.pone.0065996

Table 4. Summary of the estimate of GERD syndrome in multiple logistic regression analysis.

Reflux esophagitis (N = 6,895) Non-erosive reflux disease (N = 7,019)
Standardized Coefficient Odds Ratio (95% CI) p-value Standardized Coefficient Odds Ratio (95% CI) p-value
Age 0.159 1.02 (1.01–1.03) <0.001* −0.154 0.98 (0.97–0.99) <0.001*
Sex
 female reference reference
 male 0.426 2.37 (1.95–2.90) <0.001* −0.125 0.78 (0.66–0.91) 0.002*
BMI 0.399 1.13 (1.11–1.15) <0.001* 0.073 1.02 (1.00–1.04) 0.035*
PG-I/PG-II 0.220 1.11 (1.06–1.17) <0.001* −0.031 0.99 (0.94–1.03) 0.521
Smoking
 nonsmoker reference reference
 former smoker 0.109 1.24 (1.04–1.49) 0.019* 0.086 1.19 (0.63–1.32) 0.048*
 smoker 0.214 1.62 (1.33–1.98) <0.001* 0.139 1.36 (1.12–1.64) 0.002*
Alcohol
 rarely drinking reference reference
 usually drinking 0.143 1.34 (1.14–1.58) <0.001* 0.059 1.13 (0.98–1.30) 0.093
Coffee
 <1/day reference reference
 1–2/day −0.062 0.88 (0.74–1.04) 0.133 −0.036 0.93 (0.79–1.08) 0.336
 ≥3/day −0.081 0.84 (0.70–1.01) 0.057 −0.032 0.93 (0.79–1.10) 0.408
H. pylori
 Negative reference reference
 positive −0.482 0.35 (0.28–0.45) <0.001* 0.065 1.15 (0.94–1.40) 0.158
*

: A p-value less than 0.05 was considered statistically significant.