Figure 2. Effects of in vitro sibutramine on basal tonus activity of distal epididymal duct.

A: Tension developed in 5 min in the absence and presence of increasing concentrations of sibutramine. The data are expressed as the mean±SEM. *p<0.05, **p<0.01 vs control (ANOVA followed by Dunnett test). B: Tension developed in 5 min in the presence of sibutramine 3 µM and nifedipine 300 nM. Data are expressed as the mean±SEM. **p<0.01 vs control (Student's t- test).