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(A) Akt phosphorylation at Ser473 residue and GLUT4 protein content assessed by Western blot and (B) diacylglycerol and ceramide lipid content in skeletal muscle of lean (n = 9) and obese (n = 9) men prior to and following 12-wk endurance training. (A) p-Akt, Akt phosphorylation at Ser473; GLUT4, glucose transporter 4. Results were normalized to β-actin protein content. * P≤0.03 pre- vs. post-training (main effect).
