Table 1. Identity/similarity percentage of T. cruzi and T. brucei PARG catalytic domain.
| T. cruzi_PARG | T. brucei_PARG | |
|---|---|---|
| T. cruzi_PARG | ------ | 51.5/65.1 |
| T. brucei_PARG | 51.5/65.1 | ------ |
| A. thaliana_1_PARG | 26.8/39.1 | 26.4/38.0 |
| A. thaliana_2_PARG | 27.9/39.5 | 27.5/38.8 |
| C. elegans_1_PARG | 24.4/38.6 | 25.7/41.3 |
| C. elegans_2_PARG | 28.2/40.3 | 26.4/39.8 |
| B. taurus_PARG | 32.6/47.7 | 33.9/47.3 |
| H. sapiens_PARG | 32.9/48.8 | 34.2/47.8 |
| D. melanogaster_PARG | 33.9/46.0 | 33.7/46.6 |
| R. norvegicus_PARG | 32.9/48.8 | 33.7/47.3 |
| M. musculus_PARG | 32.9/48.8 | 33.9/47.6 |
| G. gallus_PARG | 32.3/46.5 | 35.0/47.9 |
| C . quinquefasciatus _PARG | 34.3/46.9 | 34.5/46.2 |
| D. discoideum_PARG | 33.6/49.4 | 30.9/46.2 |
| A. aegypti_PARG | 34.0/44.2 | 34.3/46.9 |
| D. rerio_PARG | 29.4/47.2 | 30.1/46.1 |
| P . abelii _PARG | 32.9/48.8 | 34.2/47.8 |
| X. laevis_PARG | 32.0/45.2 | 35.0/47.7 |
| T . thermophila _PARG | 28.7/45.9 | 26.4/43.6 |
| P . troglodytes _PARG | 32.7/48.5 | 33.2/46.2 |
T. cruzi and T. brucei PARG catalytic motif amino acid sequences were aligned with the catalytic regions of PARGs from different organisms. The optimum alignments were generated using the EMBOSS: needle online version at the European Bioinformatics Institute which applies the Needleman-Wunsch global alignment algorithm. T. cruzi PARG (accession number ABG73229); T. brucei PARG (GeneDB Systematic Name: Tb09.211.3760); C. elegans_1 PARG (accession number NP_501496) and C. elegans_2 PARG (accession number NP_501508); T . thermophila (accession number EAR94344); A. thaliana_1 PARG (accession number NP_973578); A. thaliana_2 PARG (accession number AAK72256); D. discoideum PARG (accession number XP_642024); D. melanogaster PARG (accession number NP_477321); C . quinquefasciatus PARG (accession number XP_001853435); A. aegypti PARG (accession number XP_001659301); D. rerio PARG (accession number XP_001338257); X. laevis PARG (accession number NP_001089602); G. gallus PARG (accession number XP_421502); B. taurus PARG (accession number NP_776563); R. norvegicus PARG (accession number NP_112629); M. musculus PARG (accession number NP_036090); H. sapiens PARG (accession number NP_003622); P . abelii PARG (accession number NP_001125086); P . troglodytes PARG (accession number XP_001139727).