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. 2013 Jan 30;304(12):C1141–C1149. doi: 10.1152/ajpcell.00351.2012

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Fig. 1. — Specialized proresolving mediators (SPM) in human subcutaneous adipose tissue. LC-MS/MS-based lipid mediator metabolo-lipidomics. A: multiple reaction monitoring (MRM) chromatograms. B: schematic illustration of the docosahexaenoic acid (DHA) metabolome. C and D: representative tandem mass spectra of 17S-hydroxydocosahexaenoic acid (17-HDHA) and protectin D1 (PD1) with diagnostic ions (C) and quantitation of SPM (D) in subcutaneous adipose tissue from patients with peripheral vascular disease (PVD) and controls. Rv, resolvin. Results represent means ± SE of 12–14 different individuals. *P < 0.01 vs. control.