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. 2013 Apr 4;304(11):G1002–G1012. doi: 10.1152/ajpgi.00005.2013

Fig. 5.

Fig. 5.

Transient receptor potential ankyrin 1 (TRPA1) mediates TNBS-induced CP. CP was induced by intraductal injection of TNBS in trpa1+/+ and trpa1-/- mice. HSS was decreased (A and D) and amylase activity was increased (B) in trpa1-/- compared with trpa1+/+ mice, suggesting that TRPA1 is involved in mediating inflammation in this CP model. C: no significant differences between the 2 genotypes were detected when pancreatic atrophy was measured. Values are means ± SE (n = 5–10). **P < 0.01 vs. trpa1+/+ TNBS.