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Biomarkers of acute kidney injury (AKI) after renal ischemia-reperfusion injury. A: serum creatinine 24 h before (basal) and 24 h after surgery (sham or IRI) as measured by tandem mass spectrometry (LC-MS/MS) for CRPtg and wild-type (WT) mice. B: urine albumin as measured by ELISA. *P < 0.001, one-tailed t-test, serum creatinine level was significantly greater in the CRPtg/IRI group than in WT/IRI. Sample sizes are indicated.
